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A scientist who developed a wrinkle cream has high hopes that a prime ingredient - elastin - could be used to regrow the skin on fingers and toes and to heal battlefield wounds.

Burt Ensley has been tinkering in the biological world of microbes since his graduate school days at the University of Texas in Austin in the late 1970s.

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There, the microbiologist worked on bacteria that ate mothballs, research that has led to its use in contaminated sites. He went on to discover bacteria that could make a dye called indigo, used in blue jeans.

In the 1980s, he landed his first research job at Amgen, the California biotech company that was just getting off the ground. He was working on wound-healing.

For more than a decade he's been on his own, collaborating with several biotech companies to turn his ideas into products that can save damaged skin. He's identified genes that make elastin. He's also found people who heal quickly and with fewer scars and has identified genes involved in this process

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He targeted proteins that are responsible for elastin, a compound not unlike chicken wire that holds skin together but has a stretchy quality to it.

The human body makes most of its elastin by the time of adolescence, and Ensley discovered there are at least 20, maybe even 100, different forms of elastin that the body makes.

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posted by whitediggydog